CAF has cancelled Orlando Pirates' Confederations Cup tie with Cameroon's Sable de Batie, which was scheduled to be played in Gwara, Cameroon on Sunday.
The continent's ruling body for football felt that the Buccaneers could not honour the fixture in Cameroon.
"We hereby inform you that the game has been cancelled because of the impossibility of the South African club to travel to Cameroon during this period," said a fax from CAF to the Cameroon Football Federation.
CAF added that their emergency committee will make a decision on the tie within two days.
It is the fourth time that the second leg in the deciding qualifier for the group stages has been postponed, after the first match was abandoned due to torrential rain and the next two were postponed for the same reason.
Pirates won the first leg 4-2 in Potchefstroom and the winner of the tie will join Ghana's Hearts of Oak, Cameroon's Cotonsport Garoua and Santos of South Africa in Group B.