Moroka Swallows have a score to settle with Santos, with the Cape side having beaten the Dube Birds in their last two league encounters.
The Beautiful Birds can expect to have their work cut out against a Santos team who are determined to climb out of the relegation zone.
The People's Team have become somewhat of a bogey side for Swallows in recent times, having beaten them twice in their last two Premiership encounters - towards the end of last season the Cape side inflicted a 5-1 drubbing on the Soweto outfit, while this season's first round match down in the Cape was won 1-0 by the hosts.
Santos have the quality to give any side a run for money on their day, however, their main problem this season has been consistency - some excellent performances have been mixed in with far too many mediocre displays.
One player who will be determined to leave his mark on the game is Santos striker Carlo Scott, who joined the People's Team from Swallows at the beginning of the season. Scott has not been in the best of form in front of goal, however he will be out to rectify this problem against his former team-mates.
Dube Birds coach Gavin Hunt will have a near full strength team to choose from for the game against Santos at the Rand Stadium this afternoon.
The only players missing from the Birds side are long-term injury victims Ivan Winstanley, Shaun Permall and Rufus Mokoti.
Zimbabwean winger Edzai Kasinauyo, who missed last week's game against Orlando Pirates, has recovered from his injury and is expected to play today.
Santos' experienced defender Edries Burton is aware that his team will have to be on top of their game to get something out the match.
"Swallows have shown they are an organised outfit, with a strong work ethic and a never-say-die attitude, so we will have to roll up our sleeves and get stuck in," said the veteran defender.
"We have a fully fit squad and are looking forward to the game after having been out of action for 10 days. The guys are all in a positive frame of mind, despite our position on the log."